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N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide

  • CAS No.: 1210608-43-7
  • Purity: 99%
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Good factory exports good N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide 1210608-43-7 We provide high quality N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (CAS 1210608-43-7), at a very affordable prices to our customers.

1.What is the N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide ?

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide, also known as PIM447, is a potent and selective inhibitor of PIM kinases. It is a complex organic compound with a unique molecular structure that allows it to target and inhibit the activity of PIM kinases, which play a crucial role in the growth and survival of tumor cells in various human cancers.

PIM kinases promote growth and survival of tumor cells and are expressed in a wide variety of human cancers. These kinases are potential therapeutic targets. PIM447 is a PIM kinase inhibitor.

2.What is the CAS number for N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide ?

The CAS number of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide is 1210608-43-7.

More information of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide 1210608-43-7 are:

CAS?Number

1210608-43-7

Density

1.290±0.06 g/cm3(Predicted)

Boiling Point

493.7±45.0 °C(Predicted)

PSA

80.90000

LogP

5.81740

Pka

1.35±0.70(Predicted)

3.What is the molecular formula of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide ?

The chemical formula of?N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide is C24H23F3N4O which containing 24 Carbon atoms,23 Hydrogen atoms,3 Fluorine atoms,4 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight, and the molecular weight of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide is 440.468

4.What is N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide(1210608-43-7)used for?

N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide, also known as PIM447, is a potent and selective inhibitor of PIM kinases. It is a complex organic compound with a unique molecular structure that allows it to target and inhibit the activity of PIM kinases, which play a crucial role in the growth and survival of tumor cells in various human cancers.

Relevant articles related to N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide:

Article

Source

Identification of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a potent and selective proviral insertion site of Moloney murine leukemia (PIM) 1, 2, and 3 kinase inhibitor in clinical trials for hematological malignancies

Burger, Matthew T.,Nishiguchi, Gisele,Han, Wooseok,Lan, Jiong,Simmons, Robert,Atallah, Gordana,Ding, Yu,Tamez, Victoriano,Zhang, Yanchen,Mathur, Michelle,Muller, Kristine,Bellamacina, Cornelia,Lindvall, Mika K.,Zang, Richard,Huh, Kay,Feucht, Paul,Zavorotinskaya, Tatiana,Dai, Yumin,Basham, Steve,Chan, Julie,Ginn, Elaine,Aycinena, Alex,Holash, Jocelyn,Castillo, Joseph,Langowski, John L.,Wang, Yingyun,Chen, Min Y.,Lambert, Amy,Fritsch, Christine,Kauffmann, Audry,Pfister, Estelle,Vanasse, K. Gary,Garcia, Pablo D.

, p. 8373 - 8386 (2015/11/25)

5.Good factory exports good N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide 1210608-43-7

QingDao JiChang Chemicals Co., Ltd is a quality supplier of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide 1210608-43-7.

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