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What is the Cinchonine ?
Cinchonine is white to light yellow crystal powder, while it's Molecular Formula is C19H22N2O. Cinchonine occurs in most varieties of cinchonabark (Cinchona micrantha and Rubiaceae).It is used as an antimalarial agent.
What is the CAS number for Cinchonine ?
The CAS number of Cinchonine is 118-10-5.
More information of Cinchonine 118-10-5 are:
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Synonyms |
(S)-[(5R,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-quinolin-4-yl-methanol;Quinoline alkaloid;.alpha.-Quinidine;Prestwick_501;(9S)-Cinchonan-9-ol;(S)-[(4R,5S,7S)-5-ethenyl-1-azoniabicyclo[2.2.2]oct-7-yl]-quinolin-4-yl-methanol;[(5S,7R)-5-ethenyl-1-azabicyclo[2.2.2]oct-7-yl]-quinolin-4-yl-methanol;D-Cinchonine;Cinchonan-9-ol, (9S)-;2-Quinuclidinemethanol, .alpha.-(5-vinyl-2-quinolyl)-;4-quinolyl(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol;(+)-Cinconine; |
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CAS?Number |
118-10-5 |
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Molecular Formula |
C19H22N2O |
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Molecular Weight |
294.396 |
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Density |
1.2 g/cm3 |
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Melting Point |
256-266 °C |
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Boiling Point |
464.5 °C at 760 mmHg |
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Flash Point |
234.7 °C |
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HS CODE |
29339900 |
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PSA |
36.36000 |
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LogP |
3.10250 |
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Pka |
5.85, 9.92(at 25℃) |
What is Cinchonine (118-10-5) used for?
Cinchonine is a cinchona alkaloid generally found in the bark of Cinchona officinalis plants. It is a pseudoenantiomer that is commonly employed in malaria therapy. Cinchonine is also used as an organocatalyst in many asymmetric reactions. It is a stereoisomer and pseudo-enantiomer of cinchonidine. It is structurally similar to quinine, an antimalarial drug.
InChI:InChI=1/C19H22N2O/c1-2-13-12-21-10-8-14(13)11-18(21)19(22)16-7-9-20-17-6-4-3-5-15(16)17/h2-7,9,13-14,18-19,22H,1,8,10-12H2/p+1/t13-,14-,18+,19-/m0/s1
Articles related to Cinchonine:
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Article |
Source |
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Reductive Amination Revisited: Reduction of Aldimines with Trichlorosilane Catalyzed by Dimethylformamide─Functional Group Tolerance, Scope, and Limitations |
Campbell, Joanna L. P.,Davies, Christopher D.,Ho?ek, Jan,Ko?ovsky, Pavel,Kysilka, Ond?ej,Popov, Kirill K.,Pour, Milan , p. 920 - 943 (2022/01/27) |
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An easy route to exotic 9-epimers of 9-amino-(9-deoxy) cinchona alkaloids with (8S, 9R) and (8R, 9S)-configurations through two inversions of configuration |
Wan, Jing-Wei,Ma, Xue-Bing,He, Rong-Xing,Li, Ming , p. 557 - 560 (2014/05/06) |
How to get the best price on Cinchonine?
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