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3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

  • CAS No.: 89339-17-3
  • Purity: 99%
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Cost-effective and customizable 3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester 89339-17-3 supplier

  • Molecular Formula: C17H21NO5
  • Molecular Weight: 319.357
  • Boiling Point: 416.2±45.0 °C(Predicted) 
  • Density: 1.30±0.1 g/cm3(Predicted) 

89339-17-3 Relevant articles

Synthesis and dopamine transporter binding of 2'-substituted cocaine analogs

El-Moselhy, Tarek F.,Avor, Kwasi S.,Basmadjian, Garo P.

, p. 50 - 57 (2007/10/03)

A series of 2'-substituted cocaine analo...

89339-17-3 Process route

3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester
192648-66-1

3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester
89339-17-3

3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
Conditions Yield
With hydrogenchloride; In methanol; for 48h; Heating;
94%
ecgonine hydrochloride
5796-31-6

ecgonine hydrochloride

3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester
89339-17-3

3β-[(2`-hydroxybenzoyl)oxy]-1R-(exo,exo)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Conditions
Conditions Yield
Multi-step reaction with 3 steps
1: HCl gas
2: Et3 N / benzene / 40 °C
3: 94 percent / HCl gas / methanol / 48 h / Heating
With hydrogenchloride; triethylamine; In methanol; benzene;

89339-17-3 Upstream products

  • 192648-66-1
    192648-66-1

    3-[(2'-acetoxybenzoyl)oxy]-[1R-(exo,exo)]-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

  • 5796-31-6
    5796-31-6

    ecgonine hydrochloride

  • 7143-09-1
    7143-09-1

    methyl ecgonine

  • 50-36-2
    50-36-2

    Cocaine

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