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1.What is the PRODIGIOSIN ?

Prodigiosin is a naturally occurring pigment which occurs as a product of Serratia marcescens. Pink colored pigment.

2.What is the CAS number for PRODIGIOSIN ?

The CAS number of PRODIGIOSIN is 82-89-3.

More information of PRODIGIOSIN 82-89-3 are:

3.What are another words for PRODIGIOSIN ?

Synonyms?for?PRODIGIOSIN 82-89-3:2,2'-Bipyrrole,4-methoxy-5-[(5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl]- (7CI,8CI);2-Methyl-3-amyl-6-methoxyprodigiosene; Prodigiosin; Prodigiosine

4.What is the molecular formula of PRODIGIOSIN?

The chemical formula of ?PRODIGIOSIN is?C20H25 N3 O which containing 20 Carbon atoms,25 Hydrogen atoms,3 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??PRODIGIOSIN?is 323.438.

5.What is PRODIGIOSIN (82-89-3) used for?

Prodigiosin is a naturally occurring, intensely red, tripyrrole alkaloid compound with antibiotic properties, produced by several bacteria, most notably Serratia marcescens. It possesses a broad biological profile, displaying immunosuppressive and anti-tumor properties, and is capable of inducing apoptosis and cell cycle arrest in tumor cells.
Used in Pharmaceutical Industry:
Prodigiosin is used as an immunosuppressant for its ability to modulate the immune system, as demonstrated in 2007. It acts via caspase inhibition to induce apoptosis in human primary cancer cells and upregulates p21WAF1/CIP1 expression via the transforming growth factor-β receptor pathway, as well as activating NAG-1 via glycogen synthase kinase-3β.
Used in Anticancer Applications:
Prodigiosin is used as an anti-tumor agent for its ability to selectively upregulate p21WAF/CIP1 and NAG-1, downregulate survivin expression levels, and induce mitochondria-mediated apoptosis and cell cycle arrest in tumor cells. It also prevents FADD phosphorylation and augments cisplatin-induced apoptosis, making it a potential candidate for cancer treatment.
Used in Antimicrobial Applications:
Prodigiosin is used as an antibiotic due to its activity against fungi and tumor cell lines, as well as its effectiveness against malaria. Its broad biological profile makes it a valuable compound in the development of new antimicrobial agents.
Used in Research:
Prodigiosin is used as a research tool for studying the mechanisms of apoptosis, cell cycle regulation, and immune system modulation. Its ability to block NF-κB activation and shrink tumor growth in animal models makes it an important compound for understanding the complex interactions between cells and their microenvironment.

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